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Long-term safety data are also still being collected
Chen G, Liang G, Ou J, Goldstein JL, Brown MS (2004) Central role for liver X receptor in insulin-mediated activation of Srebp-1c transcription and stimulation of fatty acid synthesis in liver
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35,36 Although some studies report smaller reductions in muscle mass, many scientists argue that these findings should not be ignored due to the high metabolic rate of skeletal muscle which plays an important role in maintaining significant weight loss