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The experimental results showed that the average Cmax ratio was 1:2.8:6.5, and the average AUC(0-t ) ratios are 1:2.8:5.7, Cmax and AUC(0-t) increase approximately in proportion to the dose increase

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When the cells in your gastrointestinal lining are not healthy, and spread too far apart, this is termed leaky gut or intestinal permeability. Leaky gut is a syndrome that was first discussed in 1965 and called the intestinal porous hypothesis