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Low protein intake, limited cysteine or glycine, selenium deficiency, mitochondrial dysfunction and poor glutathione recycling may further reduce antioxidant reserve

GHK-Cu, also known as copper peptide GHK-Cu, is a naturally occurring copper complex that has gained significant attention in research communities

According to the letter, the effects have so far been insufficiently studied in clinical settings because the trials do not last long enough

This is why dose reduction (not cessation) is often the first step when GI side effects occur partial receptor occupancy may provide benefit with reduced GI burden

Compr Rev Food Sci Food Saf 19(4):17771808

Endemann, D