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Methods Leveraging the target trial emulation framework, we conducted a retrospective study using observational data to emulate a new user, active comparator trial examining the effects of initiating GLP-1RA (exposure group) versus SGLT2 inhibitors (control group), with random treatment assignment emulated by propensity score matching with 1:1 ratio

The research citations referenced on this page relate to individual component peptides studied in preclinical or animal model settings and do not constitute evidence of safety or efficacy in humans

We therefore developed dual-GLP-1/GIP receptor agonists that can cross the BBB at an enhanced rate and showed superior protective properties on synapses in animal models of AD and PD

For women of reproductive age, the relationship between GLP-1 receptor agonists and reproductive hormones is an area of active research