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In rats undergoing Roux-en-Y gastric bypass (RYGB), transcript levels of Tlr4, Myd88, Cd14, and downstream pro-inflammatory cytokines including Il1b, Il6, Il18, and Tnfa were significantly reduced in the hypothalamus, suggesting a procedure-specific attenuation of TLR4 signaling

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Wells containing medium only were included to quantify the plate-specific fluorescence background signal

Inflammation in obesity-related HFpEF: The STEP-HFpEF Program

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Sobhiyeh S, Dunkel A, Dechenaud M, Mehrnezhad A, Kennedy S, Shepherd J, et al