Peter Sikiric, the peptide's principal investigator, has stated: "BPC-157 has demonstrated a remarkable safety profile across hundreds of experimental applications, with no observed lethal dose in any tested species and consistent organ-protective effects rather than organ-damaging ones" 1
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LL-37 in particular also promotes gingival keratinocyte migration and angiogenesis accelerating the repair of damaged gingival tissue alongside its antimicrobial function
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In addition to a medium made of 0.5 ml of DMEM, 10% FBS, 100 U/mL of penicillin, and 100 mg/mL of streptomycin, BPC 157 was added to each well in concentrations of 0 (control group), 0.1, 0.25, and 0.5 ug/mL for 1, 2, and 3 days in a humidified atmosphere