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However, these side effects have also been associated with other glucagon-like peptide 1 medications currently available for weight management

Dosing changes when kidney function is low Because the kidneys clear many substances, standard dosing may not apply when your eGFR is reduced

Weight Regain - While studies have demonstrated that GLP-1s can help people with obesity lose as much as 15-21% of their body weight, one study found that most people regained an average of 23 of the weight they lost within a year of stopping the medication and supporting lifestyle intervention

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It implies that the body is returning to a state of relying on pure natural production, which is already decreasing because of old age or stress

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