Borsani O, Valpuesta V, Botella MA
Redox metabolism: ROS as specific molecular regulators of cell signaling and function
(2015) Formation of the 18,19 double bond and bis(spiroacetal) in salinomycin is atypically catalyzed by SlnM, a methyltransferase-like enzyme, Angewandte Chemie , 54 , 9097-9100, Jansson, A., Koskiniemi, H., Erola, A., Wang, J., Mntsl, P., Schneider, G., and Niemi, J
Unlike glutathione, B12 cannot be produced by the body, meaning it must be obtained through diet or supplementation
Thats exactly where glutathione changes things
New work demonstrates how one antioxidant inside particular cellular compartments, the mitochondrial metabolite glutathione, helps cancer cells metastasize throughout the body by enabling their survival under low-oxygen conditions