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Statements Acknowledgments We apologize for not being able to cite many relevant original papers, replaced by reviews, due to space limitation

The cards below summarise the chemistry, the body's stockpile, and where each is found in the diet

Under pathological conditions, the double injury of increased MG production and decreased MG degradation in renal tissues leads to the accumulation of this toxic metabolite, which may further exacerbate renal injury

Lamos EM, Malek R, Davis SN

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