is xigduo a glp-1 XR: Package Insert / Prescribing Information / MOA Glucagon-like peptide-1 - Wikipedia

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GLP-1 drugs are a class of medications that mimic the action of the naturally occurring hormone glucagon-like peptide-1 (GLP-1)

Nothing else

They contain only semaglutide without any other ingredients

Coverage for weight loss is a different story: only 13 states cover obesity-indicated GLP-1s as of January 2026, and that number has been shrinking as states face budget pressure

Looking forward, future research should focus on long-term safety, durability of weight loss, and real-world effectiveness of GLP-1RAs across diverse populations, including those in LMICs