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This substance was first isolated and described in the scientific literature in the 1990s by a team of Croatian scientists led by Professor Predrag Sikiri

It has a molecular weight of approximately 403.9 Da in its free peptide form (or ~340.4 Da without the copper ion)

Whilst these compounds have established biochemical functions, there is no robust randomised controlled trial evidence for clinically meaningful weight loss or fat reduction in replete individuals

Research Applications Fertility research Testosterone-support investigations Hormonal-balance studies Testicular-function research This is a simplified explanation for educational purposes

The two most commonly used forms are hydroxocobalamin and cyanocobalamin