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The 15-amino-acid fragment designated BPC-157 was selected for study because it retained the cytoprotective properties of the parent protein while being amenable to chemical synthesis at research-grade purity a practical advantage that has enabled three decades of systematic preclinical investigation
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New Indications : GLP-1 drugs are being tested for obesity-related conditions (NASH/non-alcoholic steatohepatitis, cardiovascular risk reduction, etc.)
In a post-hoc analysis of the published SURPASS trials, the change in systolic blood pressure was greater for tirzepatide versus the comparators of the trials (tirzepatide 5 mg: -5.1 to -1.3 mmHg, tirzepatide 10 mg: -6.5 to -1.7 mmHg, tirzepatide 15 mg: -11.5 to -3.1 mmHg) [65]
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