, 2024) or patients receiving non-GLP-1 RA antidiabetic drugs (mostly metformin) or women with overweight/obesity without diabetes (Dao et al
Triple agonist therapy means more aggressive appetite suppression, potentially lower caloric intake, and greater lean mass loss risk
Lawsuits have accused Novo Nordisk of failing to warn about dangerous side effects associated with Ozempic, Wegovy, and Rybelsus, Lawsuits have also named Eli Lilly based on similar allegations involving Trulicity and Mounjaro
However, if weight loss is the main objective, other GLP1 options like Wegovy might provide superior results due to higher dosing for obesity management
Dual GLP-1/GIP receptor agonists possess distinct pharmacodynamic and metabolic profiles, and long-term oncological safety data for these agents remain limited
Heart rate effects peak around week 24 of treatment and then decline at weeks 36 and 48 even with continued dosing