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PMID: 37463995 EMBO RepTargeting the transcription factor YY1 is synthetic lethal with loss of the histone demethylase KDM5C

Cells either received 200 M TBHP alone or co-incubation with NAC, NACET, or diNAC at a range of concentrations, where 200 M had been previously demonstrated to be the maximum concentration to not significantly affect cell viability in ARPE-19 cells [25]

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Glutamate Homeostasis Under Depression The 1 H-MRS method has been used extensively for the assessment of glutamate and other metabolite levels in the brain of depressed subjects and rodent models of depression (Table 1)

It is frustrating to us as Patient Advocates that initial evidence relied on was not at that time suitably researched or understood and now, 30 years on, of course, we know so much more