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Current focus areas include: Genetic risk stratification in Type 2 diabetes Pharmacogenomics influencing drug response Biomarker-guided treatment intensification Continuous metabolic phenotyping However, real-world challenges persist: Cost-effectiveness Accessibility across regions Standardization of predictive models Translational gaps between research and practice The science is accelerating

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Gil-Lozano M, Prez-Tilve D, Alvarez-Crespo M, Marts A, Fernandez AM, Catalina PA, Gonzalez-Matias LC, Mallo F (2010) GLP-1(736)-amide and Exendin-4 stimulate the HPA axis in rodents and humans

Restoring testosterone levels with testosterone replacement therapy (TRT) may help offset stresss negative effects

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