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Microbiol 18 , 275285 (2020 Peng, B., Li, H

doi: 10.1016/j.cej.2024.152398 192 KongKYangYChangYChenYYangXQinJet al

Grape seed procyanidin B2 inhibits advanced glycation end product-induced endothelial cell apoptosis through regulating GSK3 phosphorylation

For silencing experiments, fully differentiated SGBS cells were transfected with 100 nM of siCtrl or sip53 (Thermo Fisher Scientific, Waltham, MA, United States) by using Lipofectamine RNAiMax (Thermo Fisher Scientific, Waltham, MA, United States) following the providers instructions

For skin brightening, some people notice changes within 2-4 weeks, while more significant improvements may take 8-12 weeks of consistent use

Ratzke and Gore, 2018)