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Treatment starts at 0.25 mg weekly and increases every four weeks through 0.5 mg, 1.0 mg, and 1.7 mg before reaching the maintenance dose of 2.4 mg per week

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The molecule contains a cysteine-linked disulfide bridge that constrains the peptide into a cyclic conformation, an important feature for maintaining its signaling profile in biochemical and adipocyte-based assays