Verify your dose is actually reaching therapeutic levels If you are still at 0.25 or 0.5 mg, you are not at a therapeutic weight loss dose
Math below assumes the research-vial protocol: 2 mg per day from a 10 mg vial reconstituted with 2.0 mL bacteriostatic water (5,000 mcg/mL concentration, 0.40 mL / 40 units per dose)
The conversion of homocysteine to methionine is of importance for homocysteine detoxification and for the production of S-adenosylmethionine (SAM), the methyl donor for the methylation of DNA and histones
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(2002) Effects of oral N-acetylcysteine on plasma homocysteine and whole blood glutathione levels in healthy, non-pregnant women