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Large clinical trials have not confirmed an increased incidence of medullary thyroid carcinoma in humans using GLP-1 medications, though these trials were not designed specifically to assess this rare outcome

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Lyophilisation, or freeze-drying, helps preserve peptide stability during storage and transport until reconstitution with bacteriostatic water

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When blood sugar is high, GLP-1 stimulates beta cells in the pancreas to produce insulin