Need a toned body
doi: 10.47957/ijpda.v12i1.568 133
I think we're basically just assuming that everything continues to be proven safe in the long run, we're kicking off a new super cycle here in pharma development around these compounds, just like played out with Insulin over the last century
For example, research from The Journal of Clinical Endocrinology & Metabolism suggests that combining GLP-1 treatment with lifestyle changes produces more sustainable weight loss than medication alone
And one of the most interesting things is that when we looked at the proteome is that we saw with the GLP-1s, what we saw was that we are actually increasing things that were really good for like mitochondrial proteins, and so thats really, really good for muscle
For example, in the tirzepatide study mentioned, 1.7% of placebo recipients reported vomiting compared to 8.3% of those taking 5mg doses, 10.7% of those taking 10mg doses, and 12.2% taking 15mg doses