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Although new protocols have been developed to improve safety, further research is necessary to refine OIT and maximize its effectiveness for managing shellfish allergies

Schmitt B, Vicenzi M, Garrel C, Denis FM (2015) Effects of N-acetylcysteine, oral glutathione (GSH) and a novel sublingual form of GSH on oxidative stress markers: a comparative crossover study

These environmental influences both alter oxidative stress response pathways in metazoans

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Interleukin 1 induces interleukin 1

While this approach may create complications in terms of attributing any demonstrated cognitive effects, assessment of the nutritional status at baseline and after supplementation will presumably help inform mechanistic questions