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Arctiin attenuates high glucose-induced human retinal capillary endothelial cell proliferation by regulating ROCK1/PTEN/PI3K/Akt/VEGF pathway in vitro

In addition, a large literature indicates that stress responses upregulate the transcription and expression of Ang II-related receptors and enhance the expression of central Ang II (144146)

PloS one 9 , e100627, doi:10.1371/journal.pone.0100627 (2014)

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Microscopically, transmural hyperemia of the gastrointestinal tract, intestinal mucosa villi reduction, crypt reduction with focal denudation of superficial epithelia, and large bowel dilatation were all inhibited

Drucker said studies have shown that GLP-1 drugs tamp down harmful inflammation, which his lab is studying