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Addressing these multisystem issues and concomitant comorbidities, such as obesity, hypertension and atrial fibrillation, that both drive the development of the condition and worsen the prognosis is essential, she said.

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[21] Those who may have adrenal fatigue, those who are often stressed, and those with the MTHFR gene variation and high homocysteine levels, may benefit from an activated or methylated version of folate, mainly because food alone does not provide sufficient levels