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Repeated inadvertent ingestion of supratherapeutic doses may be especially dangerous, due to subacute depletion of hepatic glutathione stores

In a healthy cell, mitochondria utilize the electron transport chain for oxidative phosphorylation, the main source of ATP production

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doi: 10.1016/j.ygeno.2021.01.022 70 ShuK.LiuX

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Moreover, ferroptosis is increasingly recognized as an important driver of disease pathogenesis, including but not limited to cancer, degenerative diseases, ischemic injury, and infections [25]