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The Preclinical Foundation Before human clinical trials began, the case for GLP-1 agonists in addiction was built on a robust body of animal research spanning more than a decade

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PMID: 33200892 Iorga RA, Bacalbasa N, Carsote M, Bratu OG, Stanescu AMA, Bungau S, Pantis C, Diaconu CC (2020) Metabolic and cardiovascular benefits of GLP-1 agonists, besides the hypoglycemic effect (Review)

There is also a separate safety question, distinct from efficacy: retatrutide raises resting heart rate by 5 to 10 beats per minute, which has not yet been characterised in patients who already have heart failure or irregular heartbeats

Increasing proportions of all prescribed pharmaceuticals are excreted into sewage and treated in waste water treatment plants

Some people inject GHK-Cu, which delivers a more concentrated dose than whats typically found in creams and serums