LFs therapeutic effects include mitigating CECs damage and promoting cellular repair, as demonstrated in animal models of DED (Pattamatta et al., 2013
As GSTP1 knockdown significantly increased cisplatin and carboplatin chemosensitivity in A2780 cells, we further investigated whether GSTP1 knockdown in the related platinum-resistant A2780DPP cell line (Behrens et al, 1987) could re-sensitise these drug-resistant cells to platinum-based chemotherapy
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KM mice ( n = 3) with G422 cells inoculated in their brain for 6 days were tail vein injected with BEAGA/ApoE-PDHD@ILD & R848, ApoE-PDHD@ILD & R848 or BEAGA-PDHD@ILD & R848 (500 g/kg ICG), respectively
Ad libitum energy intake during a subsequent lunch was also assessed