[DOI] [PubMed] [Google Scholar] 58.Vivas Maiques C., Martinez-Mir I., Palop L
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High levels of oxidative stress can damage cellular structures, including DNA, and have been implicated in various fertility challenges for men and women
Similarly, the small bowel transit time (SBTT) did not differ between the two groups (335.2 106.9 min vs
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We hypothesize that (i) the slow inhibition observed in the biochemical assay with the recombinant protein with some of the compounds is due to their preferential binding to a slowly populated conformer of the NADP + -TGR(H) complex and (ii) this conformer is already populated in the worm cell interior accounting for the more rapid inhibition of TGR observed in ex vivo worms with the slow inhibitors