From each subject, a detailed brain image was first acquired, using a magnetization-prepared rapid gradient echo 47 high-resolution T1-weighted sequence (repetition time=6.6 ms, echo time=3.0 ms, flip angle=8, matrix=256240, slices =170, and slice thickness=1 mm)
This principle is the fundamental reason why loading doses are necessary for drugs with very long half-lives such as for amiodarone with a t 1/2 of over 50 days
C57BL/6 J young mice (males, 8 weeks) and aged mice (males, 16 month) were used to generate the pulmonary fibrosis model
H., Dauksaite, V., Sporbert, A., Gotthardt, M
Average decreases in folic acid concentrations of 36% (dark) and 39% (light) after 6 months and 47% (dark) and 50% (light) after 12 months of storage were observed 487
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