Based on the assumption that a ternary complex is formed between PfGrx, GSH, and roGFP2 WT (S 2 ), we estimated true k red values from tertiary plots at variable GSH concentrations of 7.3 10 5 M 2 s 1 and 1.3 10 5 M 2 s 1 for PfGrx C88S and PfGrx C32S/C88S , respectively (Fig
In a single-arm clinical study of patients with metastatic angiosarcoma, the inclusion of propranolol or carvedilol in the treatment regimen resulted in a median PFS of 9 and 36 months, respectively, which was significantly longer than the survival in patients who received chemotherapy, radiotherapy, and/or surgery 66 (Table 2)
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The supernatants were filtered (0.2- m filter), transferred to glass HPLC vials, and kept at 80 C prior to performing a targeted metabolomic analysis consisting of 203 metabolite references at the UT Southwestern Medical Center Metabolomics Core Facility (Sciex QTRAP 6500 + mass spectrometer)
Steinert JR, Amal H
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