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A typical taper drops one dose level every 4 to 8 weeks

Once treatment stops, weight regain is common (Garvey et al., 2022)

They spend 60 minutes on the treadmill, then maybe 15 minutes with dumbbells as an afterthought

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Initially approved by the FDA to treat type 2 diabetes, it has started drawing interest from people without the condition who are looking for quick weight loss

Importantly, age-related adrenal changes, including increased prevalence of cortisol-secreting adenomas and altered hypothalamicpituitaryadrenal axis regulation, may contribute to a chronic state of mild glucocorticoid excess in elderly individuals