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For much of her adult life, Nora Nye, 57, a bankruptcy attorney in Denver, called her depression the black dog. It would just appear out of nowhere

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Materials and Methods Animals Four weeks-old male C57BL/6 mice (Janvier Labs, Saint Berthevin, Cedex, France) were housed in a controlled environment (12 h light/dark cycle, lights on/off at 3AM/3PM

however, when compared with the placebo, the pioglitazone therapy was not that successful (34% and 19%)

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