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Journal of Trauma Nursing 13(2):58-65

DIFFERENTIAL DIAGNOSIS Hashimoto's thyroiditis is to be distinguished from nontoxic nodular goiter or Graves' disease

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The mechanisms by which certain medications bring about oral mucosal melanin hyperpigmentation include upregulation of tyrosinase activity, deposition of complexes of the drug with pre-existing melanin in the mucosa, or induction of local inflammatory reactions with the triggering of melanin production [11, 38]

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