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Semaglutide is a prescription medication that belongs to a class of drugs known as GLP-1 receptor agonists

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Following subcutaneous injection, the peptide enters systemic circulation with bioavailability of 14-19% in rats, while intramuscular administration achieves 45-51% bioavailability in beagle dogs, indicating both route-dependent and species-dependent absorption characteristics

10.1210/en.2006-0088 51 EisenbergT.KnauerH.SchauerA.BttnerS.RuckenstuhlC.Carmona-GutierrezD.et al (2009)