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2024 Sep 26;9(1):253

Gut mucosal response to food antigens in Crohn's disease

The scope of the review is intentionally selective rather than exhaustive, focusing on peptidereceptor systems that demonstrate biological plausibility, mechanistic coherence, and unmet therapeutic potential, yet lack approved therapeutic analogs or advanced clinical programs

Saying "there are observational data in people with lupus and type 2 diabetes suggesting lower rates of adverse renal and cardiac outcomes" is accurate

Anyone considering GLP-1 for ongoing treatment should work closely with a health care professional to balance the benefits with the potential risks

Finally, long-term safety, treatment persistence, cost-effectiveness, and identification of patient subgroups most likely to benefit from dual therapy remain uncertain