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This article examines what the science and UK clinical guidance actually say about B12 supplementation and weight loss, identifies who genuinely needs B12 supplementation, outlines safe dosage according to NHS and BNF recommendations, and sets out the evidence-based weight management strategies endorsed by NICE
People taking medications that interfere with B12 absorption, including metformin or long-term acid-reducing medications, often benefit from injections
Takanashi K, Inukai T
When beginning injections to treat a B12 deficiency, as with any supplement, there may well be side effects, including: Mild diarrhoea Itching or a rash on the skin, typically where the injection was given
Where you receive the injection matters
New England Journal of Medicine , 357 (26), 26662676
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