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This architectural organization, in which ductal cells form an apical lumen, basally contacted by mesenchymal cells and embedded in the hepatocyte structure, was observed in approximately 80% of the assembloids and across donors

We next analysed the effects of modulating ferroptosis vulnerability in Iso-cBOs and treated them with a ferroptotic inducer, RSL3 and a ferroptotic inhibitor, Fer-1 (Fig

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