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Screening cellcell communication in spatial transcriptomics via collective optimal transport

Consequently, the gutkidney axis can be understood as a unified framework, mediated by immune and metabolic pathways, that links gut immunity with microbial metabolism, thereby opening new avenues for immune-modulatory strategies beyond traditional pharmacological approaches ( 3.2 Gut barrier dysfunction and endotoxin translocation The gut barrier is a complex protective system comprising physical, chemical, microbial, and immune barriers, with tight junction proteins being a critical element ( Under normal conditions, protected by tight junction proteins, the gut barrier prevents the passage of intestinal pathogens ( 3 which is hydrolyzed to NH 4 OH, raising the intestinal pH

Brown earned his Bachelor of Arts from Cornell University and his Doctorate in Osteopathic Medicine from the New York College of Osteopathic Medicine

Nat Commun 12 , 870 (2021)

Wang H, Huang Q, Xia J, Cheng S, Pei D, Zhang X, et al

Yang et al., 1999