2009 Feb-Apr;30(1-2):42-59
These pro-inflammatory mediators, along the lines of ROS, also stimulate -secretase activity and enhance the expression of amyloid precursor protein (APP), which promotes the processing of APP into the amyloid form (36)
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TKT has two active centres with one THDP molecule attached to a binding motif [98, 99] and a bivalent cation (Ca affinity more than Mg [100]) tightly bound at each centre by noncovalent interactions [101]
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GLP-1 receptors are also widely distributed in the hypothalamus, and their activation enhances satiety, which leads to a decrease in calorie intake and consequently weight reduction [25]
