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The broad-spectrum thioesterase inhibitor palmostatin B also has off-target effects and poor drug specificity, leading to a lack of stability, thus limiting its clinical use (249, 250)

Its such a nice little self-care treat, and Im already looking forward to my next session

George Eid, chair of the Bariatric and Metabolic Institute at Allegheny Health Network

doi: 10.1073/pnas.91.21.9765

But competition is coming from amylin agonists, which bring unique advantages that could position them to overtake GLP-1 as the preferred monotherapy or combination backbone without simply pushing for a bigger weight loss number

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