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Isoprostanes and neuroprostanes as biomarkers of oxidative stress in neurodegenerative diseases

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Nogueras, L

Neurodegenerative Disease & Aging GSH levels decline with age and in neurodegenerative conditions, including Alzheimers, Parkinsons, and Huntingtons disease, in addition to stroke

Researchers should note that AOD-9604 completed Phase II clinical trials under the pharmaceutical development programme of Metabolic Pharmaceuticals before the programme was discontinued

We also observed increased aggregate formation following incubation of the GST fusion proteins with cell lysate, which appears to depend on both the cell type and experimental conditions