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[27] Additionally, anyone with Lebers hereditary optic neuropathy (a rare inherited eye disease) must avoid cyanocobalamin injections, since B can precipitate rapid worsening of that condition
Most people notice improved energy or reduced deficiency symptoms within a few days to weeks, but results vary
Let this act as a guideline for you: Oral capsules 400-1,000 mcg per day (if using an isolated B12 supplement) Sublingual B12 1,000-5,000 mcg per day
If you follow a vegan diet, B12 is not found naturally in fruit, vegetables or grains, so fortified foods or a supplement matter more, and seaweed, spirulina and similar products are not reliable sources
however, recent studies have proposed that it may promote restful sleep