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Since Ca 2+ -dependent exocytosis of GLP-1 from L-cells is stimulated by ingested nutrients 17,18,19 , orally administered JWU-A021 might activate intestinal TRPA1 channels so that it replicates the GLP-1 secretagogue effect of such nutrients

ElrashidyRAKavranMAskerMEMohamedHEDaneshgariFLiuG.Smooth muscle-specific deletion of MnSOD exacerbates diabetes-induced bladder dysfunction in mice

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H., & Hegde, V

Appetite perception Perceptions of satiety, hunger, fullness, desire to eat, prospective consumption, and nausea were quantified using validated 100-mm VAS questionnaires [15]