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The good news is that this inflammatory phase typically resolves as weight stabilizes and exercise habits improve

Phase 2 CagriSema in T2D (Frias et al., 2023): CagriSema produced superior weight loss and glycemic improvement vs either monotherapy over 32 weeks

Stick to bland, easily digestible foods like soups, lean chicken, rice, or steamed vegetables

That insight eventually led to formulas designed to tap into those same repair pathways

A gut-selective dose of sitagliptin reduced lipid excursion and increased active GLP-1 levels in Dpp4 EC+/+ mice but not in Dpp4 EC/ mice, although plasma DPP-4 activity was decreased by approximately 20% in both genotypes (Figure 3, AD)

Oral semaglutide, sold as Rybelsus, is approved for the treatment of type 2 diabetes