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It is becoming a metabolic disease platform where obesity, glycemic control, cardiovascular risk, kidney protection, liver fat reduction, sleep apnea and long-term adherence are increasingly linked

J Clin Investig 116(2):299302 Schroeder EB (2022) Management of type 2 diabetes: selecting amongst available Pharmacological agents

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These include different GLP-1/GIP combinations with varying receptor affinity profiles, triple agonists that add glucagon activity, and oral formulations of dual agonists

Brand-name GLP-1 medications comprised 68% of the current use compared with 19% for compounded or custom-mixed versions