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Personal or family history of medullary thyroid carcinoma, multiple endocrine neoplasia type 2, severe pancreatitis, and severe kidney disease are key exclusions

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In either event, the fact remains: Vitamin B12 is a serious deficiency that can lead to multiple negative side effects

The KFRE is a formula predicting the likelihood of progression to ESKD with the need for dialysis or transplantation over time (in years)

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