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Yazdani, A, Yazdani, A, Mndez-Girldez, R, Pillonetto, G, Samiei, E, Hadi, R, Lenz, HJ, Venook, AP, Samiei, A, Nixon, AB, Lucci, JA, Kopetz, S , Bertagnolli, MM, Innocenti, F
von Herrath M, Bain SC, Bode B, Clausen JO, Coppieters K, Gaysina L, et al (2021) Anti-interleukin-21 antibody and liraglutide for the preservation of -cell function in adults with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled, phase 2 trial
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The inability of the multi-agonists to restore gonadal function in PWA mice is likely due to chronic exposure to fixed concentrations of the exogenous androgen, DHT, which may limit the eventual beneficial effects of the compounds at the gonadal level, even when substantial metabolic improvements are achieved
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