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Provisional Applications 60/594,996 filed on May 25, 2005 with the title The Use Of A Liposomal Formulation For Oral Administration Of Glutathione (Reduced) And/Or Methylcobalamine In The Treatment Of Diseases Related To Glutathione Deficiency And Deficiency Of The Methionine Remethylation Pathway and 60/803,074 filed on May 24, 2006

Berberine primarily affects intracellular energy metabolism and may have direct effects on glucose transporters and insulin signalling

In sachet form

Kiyosue, A

Dosing adjustments or discontinuation may be needed if severe side effects develop

Formulation complexity: More comprehensive formulations with additional ingredients cost more