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ClinicalTrials.gov TRIUMPH-4: A Study of Retatrutide (LY3437943) in Participants With Obesity and Knee Osteoarthritis (NCT05929066)

Glucagon adds a third mechanism: increased energy expenditure through hepatic lipid oxidation and thermogenesis

When people stop these medications, it's not just the weight that can come back there's also a resurgence in inflammation, blood pressure and cholesterol

Considering the growing burden of obesity and diabetes, there has been a rise in the need for safe and effective medications

This can help to delay the increase in blood glucose levels after eating, decrease insulin secretion and therefore help to reduce the risk of reactive hypoglycaemia

But rapid weight changes can tax your immune function