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Lawrence, E

Micronutrients Micronutrients are essential dietary elements, required to orchestrate a range of physiological functions important for development and maintenance of a healthy brain [92]

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Studies have shown that glutamate exposure or hypoxia/ischemia can trigger the activation of extrasynaptic NMDARs, activate the shutdown of cAMP response element-binding protein (CREB), and lead to mitochondrial membrane-potential loss and cell death (Figure 1)

Patent activity highlights curcumin-, resveratrol-, and quercetin-based nanosystems, such as liposomes, polymeric nanoparticles, and plant-derived vesicles, designed for improved solubility, stability, and tumor targeting (Table 1)