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Subsequent work by Pickart and Margolina identified clusters of affected genes spanning DNA repair, antioxidant defense, ubiquitinproteasome activity, anti-inflammatory signaling, and tissue remodeling [2]

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Thats not part of the pathophysiology. And yet, if a medication is approved for OTC sales, it has already cleared a safety threshold, and the consumer doesnt need to parse clinical trial data or find a willing prescriber

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